Cranberex® – Cranberry Extract
Cranberex® is a concentrated, standardized Cranberry extract that represents a powerful advance in the delivery of Cranberry’s most active constituents.
Overview
Cranberex’s unique proanthocyanidins (PAC’s) containing the ‘A-type’ linkages that don’t occur in PAC’s from other tannin rich foods. It is this high concentration of unique PAC’s that focuses and connects Cranberex® to the latest analytical methods and clinical trials that demonstrate Cranberry’s exceptional abilities to support urinary tract health.
Ingredient Solution
- Urinary tract health
Key Features
- Pure whole berry Oregon Cranberry extract (200:1)
- Comparative testing shows 10 – 15 times more active constituents than leading raw material brands*
- Test results from Rutgers University show exceptional anti-adhesion activity, as compared to other brands*
- Levels of ‘A-Type’ PAC’s in Cranberex™ correspond to most effective clinical trials of Cranberry extracts with a dose of 240mg – 480mg.
Clinical trials & Science behind Cranberex
1 – In-Vitro Anti-Adhesion Activity (AAA) data from Rutgers University*
This in-vitro study compared the AAA of Cranberex® with nine other brands of cranberry extract (raw material and finished products). In this study, Cranberex™ met the anti-adhesion criteria at a concentration of only 0.23mg/mL. The next most potent brand required a concentration of 60mg/mL to achieve the same anti-adhesion result. The study concluded that Cranberex™ had excellent anti-adhesion activity.
2 – Ex-Vivo AAA study from Rutgers University*
This study, was designed to test AAA activity in the urine after consumption of standard dosage of Cranberex.® The study found that AAA response increased rapidly in all participants 3 – 6 hours after consumption of Cranberex®. Half of the participants achieved 100% or significant bacterial Anti-Adhesion Activity, while half achieved 50%, resulting in an average of 75% AAA. (see fig 2).
3 – Cranberex™ dosage level
The recent, multicentric randomized, double blind clinical trial clearly affirmed a bacterial anti-adhesion effect in urine, based upon 36mg/day of cranberry PAC (by BL-DMAC method) [3]. It also reported that effectiveness was dose-dependent, prolonged up to 24 hours with 72 mg of PAC, and increasing with the amount of PAC (by BL-DMAC method) consumed.
4 – Comparative potency testing
Tests that compared PAC levels in Cranberex™ with five leading finished product brands, showed a far greater potency in Cranberex™ (see fig 1).