Advancing age leads to a decline in the body’s levels of nicotinamide adenine dinucleotide (NAD) due to reduced NAD production and faster NAD degradation (1-3). 

In 2013, David Sinclair, a professor of genetics at Harvard University, made a breakthrough in anti-aging research. He found that older rats had lower NAD + levels than younger herds. He added Nicotinamide mononucleotide (NMN) to the drinking water of old rats. In just one week he saw that their muscles and DNA repair ability had returned to the level of young rats.

Nicotinamide mononucleotide (NMN) is a naturally occurring compound in the body that plays a vital role in how cells use energy. It is involved in the synthesis of nicotinamide adenine dinucleotide (NAD), a coenzyme in cells that is essential for converting energy from nutrients into a form cells can use. NMN increases NAD which in turn activates a protein called SIRT1 to promote healthy metabolism throughout the body, particularly from the pancreas to the liver, and to muscles and fat tissue.